针刺联合杞菊地黄丸治疗肝肾亏虚型干眼症49例临床观察

Clinical effect of acupuncture combined with Qiju Dihuang pills in treatment of xerophthalmia with deficiency of liver and kidney:an analysis of 49 cases

目的:观察针刺联合杞菊地黄丸治疗肝肾亏虚型干眼症的临床疗效。方法:将90例肝肾亏虚型干眼症患者随机分为治疗组与对照组各49例,治疗组采用针刺联合杞菊地黄丸治疗,对照组采用右旋糖酐羟丙甲纤维素滴眼液治疗。观察比较2组临床疗效和泪膜破裂时间和泪腺分泌量。结果:总有效率治疗组为91.8%,对照组为61.2%,2组比较,差异有统计学意义(P<0.01);2组泪膜破裂时间和泪腺分泌量治疗前后组内比较和治疗后组间比较,差异均有统计学意义(P<0.05)。结论:针刺联合杞菊地黄丸治疗肝肾亏虚型干眼症有较好的临床疗效。

Objective： To investigate the clinical effect of acupuncture combined with Qiju Dihuang pills in the treatment of xerophthalmia with deficiency of liver and kidney. Methods： A total of 90 patients with xerophthalmia with deficiency of liver and kidney were randomly divided into treatment group and control group,with 49 patients in each group. The patients in the treatment group were given acupuncture combined with Qiju Dihuang pills,and those in the control group were given dextran hydroxypropyl methylcellulose eye drops. The two groups were compared in terms of clinical outcome,tear break-up time,and lacrimal secretion volume. Results： There was a significant difference in the overall response rate between the treatment group and the control group（ 91. 8% vs61. 2%,P〈0. 01）. Both groups had significant changes in tear break-up time and lacrimal secretion volume after treatment,and there were significant differences in tear break-up time and lacrimal secretion volume between the two groups after treatment（ P〈0. 05）. Conclusion： Acupuncture combined with Qiju Dihuang pills has a good clinical effect in the treatment of xerophthalmia with deficiency of liver and kidney.