阿伐斯汀联合玉屏风颗粒治疗慢性荨麻疹临床研究

Efficacy of acrivastine combined with yupingfeng grain in the treatment of chronic urticaria

目的:评价阿伐斯汀胶囊联合玉屏风颗粒治疗慢性荨麻疹的疗效及安全性。方法:将入选的63例慢性荨麻疹患者分为治疗组(34例)和对照组(29例)。治疗组患者口服阿伐斯汀胶囊联合玉屏风颗粒,对照组口服阿伐斯汀胶囊。结果:治疗4周后,治疗组症状体征评分为2.2±1.6,明显低于对照组的3.9±2.1,差异有统计学意义(P<0.05)。治疗组有效率为70.58%,高于对照组的48.27%,差异有统计学意义(P<0.05)。两组患者均未见明显不良反应。结论:阿伐斯汀胶囊联合玉屏风颗粒治疗慢性荨麻疹疗效优于单用阿伐斯汀胶囊。

Objective： To assess the efficacy and safety of acrivastine capsules combined with yupingfeng grains in the treatment of chronic urticaria. Methods： Sixty-three patients were randomly divided into the treatment group（ 34 patients） and the control group（ 29 patients）. All the patients were treated with oral acrivastine capsules and the patients in the control group were treated with additional yupingfeng grains. Results： After 4 weeks treatment,the total score of the signs and symptoms in the treatment group was 2.2±1.6,which was lower than that in the control group（ 3.9±2.1）,with a significant difference（ P0.05）. The effective rate in the treatment group was 70. 58%, which was higher than that in the control group（ 48.27%）,with a significant difference（ P0.05）. There was no obvious adverse reactions in both groups of the patients. Conclusion： Acrivastine capsules combined with yupingfeng grains is more effective than acrivastine capsules alone in the treatment of chronic urticaria.