自拟养胃护心汤对慢性心力衰竭患者症状缓解期食欲减退的疗效观察

Curative Efficacy of Self-made Yangwei Huxin Decoction in the Treatment of Anorexia of Chronic Heart Failure Patients at Symptomatic Remission Stage

目的:运用宗气理论自拟养胃护心汤治疗慢性心力衰竭(CHF)胃阴亏虚型患者。方法:选取2013年9月至2016年9月,本院收治的100例慢性心力衰竭缓解期食欲减退患者随机分为2组,观察组对照组各50例。对照组给予西医常规治疗,观察组在西医常规治疗基础上加用养胃护心汤。观测2组患者左心室射血分数,血清胃泌素及胃动素浓度,中医证候积分、明尼苏达心力衰竭生命质量调查表、6 min步行试验。结果:养胃护心汤加西医常规观察组在左心室射血分数,血清胃泌素及胃动素浓度,改善胃阴亏虚证候、生命质量评分、6 min步行试验优于对照组(P<0.05)。结论:用宗气理论自拟养胃护心汤治疗慢性心力衰竭(CHF)胃阴亏虚型患者,可通过增强心脏功能,促进胃肠道激素分泌等方式,改善慢性心力衰竭胃阴亏虚型患者症状,提高患者生命质量。

Objective： To apply the self-made Yangwei Huxin Decoction to treat chronic heart failure patients of stomach yin deficiency type by the theory of pectoral qi. Methods： A hundred cases with anorexia of CHF patients were selected and divided into control group（ n = 50） and treatment group（ n = 50） according to the different treatments. Patients in the control group received conventional western medicine treatment,while patients in the treatment group additionally received Yangwei Huxin Decoction.The left ventricular ejection fraction,serum gastrin and motilin concentration,TCM syndrome score,Minnesota questionnaire on quality of life for heart failure and 6-minute-walk test were observed in the two groups. Results： The left ventricular ejection fraction,serum gastrin and motilin concentration,improvement in symptoms of the stomach yin deficiency type,quality of life scores and 6-minute-walk test of treatment group were better than those of the control group（ P 0. 05）. Conclusion： With the theory of pectoral qi,Yangwei Huxin Decoction in the treatment of anorexia of patients with chronic heart failure at symptomatic remission stage may enhance heart function,promote gastrointestinal hormone secretion,improve symptoms of patients and the quality of life of patients.