摘要
Hydrogels have drawn considerable attention in the past two decades due to their excellent biocompatibility and multi-stimuli responsiveness. They have a wide range of applications in the fields related to tissue engineering, sensors and biomedicine. Their applications are strongly influenced by the surface properties of hydrogels and the interfacial interactions between hydrogels and other substrates. In particular, the surface wettability and adhesion of hydrogels decide their applications as drug carriers and wound dressing materials. Nevertheless, there is a lack of systematic discussion on the surface functionalization strategies of hydrogels. Therefore, this review aims at summarizing the strategies of functionalizing the surfaces of hydrogels and bonding hydrogels with other solid substrates. It also explores the challenges and future perspectives of interfacial engineering of hydrogels.
Hydrogels have drawn considerable attention in the past two decades due to their excellent biocompatibility and multi-stimuli responsiveness. They have a wide range of applications in the fields related to tissue engineering, sensors and biomedicine. Their applications are strongly influenced by the surface properties of hydrogels and the interfacial interactions between hydrogels and other substrates. In particular, the surface wettability and adhesion of hydrogels decide their applications as drug carriers and wound dressing materials. Nevertheless, there is a lack of systematic discussion on the surface functionalization strategies of hydrogels. Therefore, this review aims at summarizing the strategies of functionalizing the surfaces of hydrogels and bonding hydrogels with other solid substrates. It also explores the challenges and future perspectives of interfacial engineering of hydrogels.
基金
financially supported by the National Natural Science Foundation of China(No.21574004)
Xiamen Southern Oceanographic Center(No.14GQT61HJ31)
the 111 project(No.B14009)
the Fundamental Research Funds for the Central Universities
the National ‘Young Thousand Talents Program’
the Academic Excellence Foundation of BUAA for PHD Students
