高龄孕妇孕早期及孕晚期血糖血脂水平对围产结局的影响研究

Research on Effect of Blood Glucose and Blood Liquid Levels in Early Pregnancy and Late Pregnancy of Senile Pregnant Women on the Perinatal Outcomes

目的探析高龄孕妇孕早期及孕晚期血糖血脂水平对围产结局的影响。方法方便选取该院2015年7月—2016年6月期间收治的300名产妇,将150名高龄孕妇设立为观察组,150名适龄孕妇设立为对照组,两组孕妇均给予血糖、血脂水平检测,比较分析两组血糖(FBG)、血脂(TG、TC、LDL、HDL)水平对母婴结局的影响。结果观察组孕晚期组血清TG(3.67±1.42)mmol/L、TC(6.68±1.03)mmol/L、LDL(3.78±1.02)mmol/L、HDL(2.42±0.42)mmol/L、FBG(4.34±0.25)mmol/L水平与对照组孕晚期组比较差异有统计学意义(P<0.05);观察组妊娠糖尿病8.00%、子痫前期27.33%、胎儿窘迫19.33%,胎膜早破14.67%,早产10.67%,剖宫产53.33%、产后出血31.33%与对照组比较差异有统计学意义(P<0.05)。结论对高龄孕妇妊娠期应重点监测血脂、血糖,及时发现异常、及时干预,能显著改善围产结局。

Objective To study the effect of blood glucose and blood liquid levels in early pregnancy and late pregnancy of senile pregnant women on the perinatal outcomes. Methods Convenient selection 300 cases of delivery women admitted and treated in our hospital from July 2015 to June 2016 were selected and divided into two groups with 150 cases in each, the observation group were the senile pregnant women, while the control group were pregnant women of the right age, and the blood glucose and blood liquid levels of the two groups were tested and the FBG and TG, TC, LDL, HDL levels on the maternal and infant outcomes were analyzed and compared. Results The serum TG, TC, LDL, HDL and FBG levels in the late pregnancy in the observation group were respectively(3.67±1.42)mmol/L,(6.68±1.03)mmol/L,(3.78±1.02)mmol/L,(2.42±0.42)mmol/L and(4.34±0.25)mmol/L, and the differences in these indexes between the observation group and the control group were statistically significant(P <0.05), and the incidence rates of gestational diabetes, preeclampsia, fetal distress,premature rupture of fetal membranes, premature labor, cesarean section and postpartum hemorrhage were respectively8.00%, 27.33%, 19.33%, 14.67%, 10.67%, 53.33% and 31.33%, and the differences were statistically significant(P<0.05).Conclusion The intensive monitoring of blood liquid and blood glucose of senile pregnant women during the pregnancy period and discovery of abnormalities and timely intervention can obviously improve the perinatal outcomes.