绝经后妇女泌尿系感染反复发作患者小剂量雌激素预防治疗的临床疗效观察

Clinical efficacy of low-dose estrogen prophylaxis in postmenopausal women withrecurrent episodes of urinary tract infection

目的 探究绝经后妇女泌尿系感染反复发作患者使用小剂量雌激素预防治疗的临床疗效.方法 选取2014 年10 月至2015年10 月间我院收治的泌尿系感染反复发作的绝经后妇女74 例,按照SPSS18.0 统计分析系统产生的随机表分为实验组和对照组,实验组患者采用小剂量雌激素进行预防治疗,对照组患者采用抗生素进行治疗,比较两组患者的治疗效果.结果 实验组患者的治疗总有效率为94.6%,复发率为10.8%;对照组患者的治疗总有效率为75.7%,复发率为40.5%;实验组患者的治疗总有效率高于对照组,且复发率低于对照组,差异有统计学意义（P 〈 0. 05）.结论 绝经后妇女泌尿系感染反复发作患者采用小剂量雌激素进行治疗,可以提高治疗效果,降低复发率.

Objective To investigate the clinical efficacy of low-dose estrogen prophylaxis in postmenopausal women withrecurrent episodes of urinary tract infection. Methods A total of 74 patients with recurrent episodes of urinary tract infectionwere enrolled in our study from October 2014 to October 2015. All subjects were randomized into the experimental group andthe control group according the SPSS18.0 statistical analysis. The treatment group was treated with low-dose estrogen, andthe control group was received with antibiotics. The clinical efficacy was compared between the two groups. Results The totaleffective rate was 94.6% and the recurrence rate was 10.8%. The total effective rate was 75.7% and the recurrence rate was40.5% in the control group. The total effective rate of the patients in the experimental group was higher than that in the controlgroup, and the recurrence rate was lower than that of the control group. The difference was statistically significant （P〈0.05）.Conclusion Low-dose estrogen can improve the clinical efficacy and decrease the recurrence rate of postmenopausal womenwith recurrent urinary tract infection.