重型颅脑损伤开颅术后患者早期进行高压氧治疗的效果观察

Observation on the effect of hyperbaric oxygen therapy in patients with severecraniocerebral injury after craniotomy

目的 研究分析重型颅脑损伤开颅术后对患者早期进行高压氧治疗的临床治疗效果.方法 选取2011 年1 月～ 2016 年1月我院收治的重型颅脑损伤实施开颅手术患者78 例,随机将患者分为观察组与对照组,每组39 例.对照组患者术后采用常规处理方式,观察组在常规处理的同时给予早期高压氧治疗,对比分析两组患者的临床疗效和并发症率.结果 观察组疗效明显优于对照组,（P 〈 0.05）差异具有统计学意义.观察组不良反应发生情况低于对照组,（P 〈 0. 05）差异具有统计学意义.结论重型颅脑损伤患者术后在常规处理的基础上再加入早期高压氧治疗,有助于提高患者的临床治疗效果,降低并发症的发生.

Objective To investigate the clinical effect of hyperbaric oxygen therapy in patients with severe craniocerebralinjury after craniotomy. Methods A total of 78 patients with craniotomy were enrolled in our study from January 2011 toJanuary 2016. All subjects were randomized into the observation and control groups, 39 cases in each group. The controlgroup was treated with conventional therapy. The observation group was treated with conventional treatment combined withearly hyperbaric oxygen therapy. The clinical efficacy and complications rate were compared between the two groups. ResultsThe efficacy in the observation group was significantly better than the control group, the difference was statistically significant（P〈0.05）. The incidence of adverse reactions in the observation group was lower than that in the control group, the differencewas statistically significant （P〈0.05）. Conclusion The conventional treatment combined with early hyperbaric oxygen therapycan improve the clinical efficacy of patients with severe craniocerebral injury, and reduce the incidence of complications.