防治宫缩乏力性产后出血的临床用药研究进展

Research Progress of Clinical Medication in Prevention and Treatment of Uterine Atony Postpartum Hemorrhage

宫缩乏力性产后出血是产妇围术期的常见并发症,轻者导致子宫切除,重者直接导致产妇死亡。近些年来由于宫缩药物的不断问世,产后出血导致的孕产妇围术期死亡率显著下降。但宫缩药物种类繁多,孕妇个体差异较大,国内外对宫缩药物的选择及使用方法、使用剂量没有统一的标准,由宫缩药物滥用所带来的不良反应的发生却有所增加。本文针对临床常用的防治宫缩乏力性产后出血的药物作一综述,为临床实践提供参考。

Uterine inertia postpartum hemorrhage is a common complication in maternal perioperative stage. It leads to hysterectomy,even maternal death directly. In recent years,due to advent of the uterine contraction drugs,the perioperative mortality rate caused by maternal postpartum hemorrhage decreased significantly. However,the occurrence of adverse reactions have increased caused by the abuse of uterine contraction drugs because of a various of uterine contraction drugs,individual differences among pregnant women,and a lack of criteria to guide their selection and uasage of uterine contraction drugs both in China and abroad. In this paper,we reviewed the commonly used drugs for the prevention and treatment of postpartum hemorrhage caused by uterine atony,and provided the reference for clinical practice.