高压氧联合神经节苷脂治疗对颅脑外伤的神经保护作用

Effect of High Pressure Oxygen and Ganglioside Treatment on the Nerve Protection of Cerebral Trauma

目的对高压氧联合神经节苷脂治疗对颅脑外伤的神经保护作用的临床效果进行研究观察分析。方法方便选取该院2013年12月—2016年10月收治的92例颅脑损伤患者,根据治疗方式不同分为对照组与观察组,平均每组46例。对照组给予常规治疗,观察组给予高压氧联合神经节苷脂治疗治疗,对比两组临床效果并观察分析。结果对照组总治愈率为28.26%,死亡率为19.57%。观察组总治愈率为47.82%,死亡率为4.35%,两组间数据对比差异有统计学意义(P<0.05)。治疗前两组患者GCS评分与Barthel指数对比差异无统计学意义(P>0.05),治疗后观察组GCS评分与Barthel相比较对照组均有所提升,组间比较差异有统计学意义(P<0.05)。结论经过高压氧联合神经节苷脂治疗对颅脑外伤的神经保护作用效果确切,患者神经功能恢复快,且接受度高,适用于各临床颅脑损伤患者,值得各医院推广及应用。

Objective To research the effect of high pressure oxygen and ganglioside treatment on the nerve protection of cerebral trauma. Methods 92 cases of patients with cerebral trauma admitted and treated in our hospital from December2013 to October 2016 were convenient selected and divided into two groups with 46 cases in each, the control group adopted the routine treatment, while the observation group were treated with high pressure oxygen and ganglioside, and the clinical effect was compared and observed. Results The differences in the total cure rate and death rate between the control group and the observation group were statistically significant(28.26%, 19.57% vs 47.82%, 4.35%)(P<0.05), before treatment, there were no obvious differences in the GCS score and Barthel index between the two groups(P>0.05), after treatment, the GCS score and Barthel index of the two groups were improved and the difference was statistically significant(P<0.05). Conclusion The effect of high pressure oxygen and ganglioside treatment on the nerve protection of cerebral trauma is definite with rapid nerve function and high acceptance, which is suitable for various patients with cerebral wounds, and it is worth promotion and application.