155例溃疡性结肠炎临床及内镜下特点分析

Analysis of Clinical and Endoscopic Features of 155 Cases of Patients with Colitis Gravis

目的分析溃疡性结肠炎患者的临床特点以及内镜下特点表现。方法回顾性分析该院2013年1月—2016年6月收治的155例溃疡性结肠炎患者的临床资料,所有患者进行内镜检查,观察所有患者临床表现以及内镜下特点。结果 155例患者30岁以下33例,占到21.3%,30~60岁70例,占到45.2%,60岁以上52例,占到33.5%。30~60岁是溃疡性结肠炎的高发年龄。0级1例(0.6%),I级59例(38.1%),II级24例(15.5%),III级23例(14.8%),IV级48例(31.0%),临床分级和内镜分级密切相关。内镜下可分为直肠炎4例(2.6%),左半结肠炎48例(31.0%),全结肠炎68例(43.9%)。该组32例患者处于临床缓解期,29例患者处于内镜缓解期,19例患者虽达到临床缓解,但内镜下观察仍然存在活动性炎症,内镜下缓解期患者共3例复发,复发率达到10.3%。结论 UC临床分级和内镜分级密切相关,内镜检查有助于临床判断缓解期患者黏膜是否愈合。但内镜下黏膜愈合患者复发率和病理检查结果之间的关系、病理分型关系还需要进一步深入研究。

Objective To analyze the clinical features and endoscopic manifestations of patients with colitis gravis. Methods 155 cases of patients with colitis gravis admitted and treated in our hospital from January 2013 to June 2016 were selected and all patients underwent the endoscopic examination, and the clinical manifestations and endoscopic features of all patients were observed. Results Of 155 cases of patients, there were 33 cases below 30 years old, accounting for 21.3%, 70 cases aged from 30 to 60, accounting for 45.2%, 52 cases aged more than 60 years, accounting for 33.5%, and 30~60 years old is the high-attack age of colitis gravis, and there was 1 case in 0 level(0.6%), 59 cases in I level(38.1%), 24 cases in II level(15.5%), 23 cases in III level(14.8%) and 48 cases in IV level(31.0%), and the clinical graduation was closely related to the endoscopic classification, and the patients were divided into 4 cases with proctitis(2.6%), 48 cases with left colonitis(31.0%) and 68 cases with pancolitis(43.9%), and in this group, there were 32 cases in the clinical relief period, 29 cases in the endoscopic relief period, 19 cases were still with active inflammatory under the endoscope, and3 cases recurred in the endoscopic relief period, and the recurrence rate reached 10.3%. Conclusion The UC clinical classification is closely correlated with the endoscopic classification, and the endoscopic examination contributes to determining whether the mucous membrane is healed or not in the clinical relief stage, we still need to further study the correlation and pathological typing correlation between the recurrence rate and pathological examination results of patients with endoscopic mucosal healing.