我院儿童病院2012-2016年处方合理性评价

Evaluation of Prescription Rationality in Children's Branch of Our Hospital during 2012-2016

目的:为儿科临床合理、有效、经济用药提供参考依据。方法:随机抽取我院儿童病院2012年5月-2016年4月处方9 771份,对处方用药品种类、处方金额、注射剂使用率、基本药物使用率、临床诊断、不合理用药情况、抗菌药物使用情况等进行统计分析。结果:在9 771张处方中,平均每张处方用药2.91种,平均处方金额77.10元,注射剂使用率为57.11%,国家基本药物使用率为67.80%。临床诊断以呼吸道疾病为主(84.17%)。不合理处方284张(2.91%),其中不规范处方156张、不适宜处方165张、超常处方65张。抗菌药物使用率为18.25%,其中头孢西丁钠注射液使用率(15.48%)最高,但其药物利用指数(0.58)较低。支气管炎患者微生物送检率(45.10%)较低。结论:我院儿童病院处方合格率高于原卫生部处方合格率>95%的规定,抗菌药物使用率和注射剂使用率较高。今后还应加强处方点评工作,促进处方规范与合理用药,保证临床用药安全、有效、经济。

OBJECTIVE： To provide scientific reference for rational, effective and economical drug use in pediatric depart- ment. METHODS： A total of 9 771 prescriptions were randomly selected from children＇ s branch of our hospital during May 2012-Apr. 2016. Those prescriptions were analyzed statistically in respects of drug type, prescription cost, utilization rate of injec- tion, utilization rate of essential medicine, clinical diagnosis, irrational drug use, use of antibiotics, etc. RESULTS： Among 9 771 prescriptions, 2.91 types of drugs were used in each prescription, and each prescription expended 77.10 yuan; utilization rate of in- jection was 57.11%, and that of national essential medicine was 67.80%. Respiratory tract disease was main disease （84.17%）. There were 284 irrational prescriptions （2.91% ）, including 156 non-standard prescriptions, 165 unsuitable prescriptions and 65 ex- traordinary prescriptions. Utilization rate of antibiotics was 18.25%, among which that of Cefoxitin sodium injection was the high- est （15.48%）, but its utilization index was the lowest （0.58）. The detection rate of microorganism isolated from bronchitis patients was in low level （45.10%）. CONCLUSIONS： The rate of qualified prescription in the children＇s branch of our Hospital is higher than the requirement of the former Ministry of Public Health concerning the rate of qualified prescription 〉95% ; utilization rate of antibiotics and injection are both in high level. In the future, it is necessary to strengthen prescription evaluation and promote stan- dard and rational use of drugs so as to guarantee safe, effective and economical use of drugs in clinic.