临床药师在儿童危重症抗感染治疗中的药学服务探讨

Investigation of Pharmaceutical Care for Pediatric Severe Infection Treatment by Clinical Pharmacists

目的:探讨临床药师在儿童危重症抗感染治疗中的作用,为临床合理用药提供参考。方法:结合相关典型案例,介绍临床药师在儿童危重症抗感染治疗决策制订中的药学服务切入点。结果:临床药师可以结合病原微生物学检查结果制订多药耐药病原菌抗感染治疗方案、以药动学/药效学为工具优化抗感染用药方案、排除药品不良反应对儿科抗感染治疗的干扰,以及在充分遵循指南的同时兼顾患儿家庭的经济因素为切入点,为医师提出切实可行的抗感染治疗方案。结论:临床药师运用自身所掌握的药学专业知识,在儿童危重症抗感染治疗中开展药学服务,可充分发挥专业协助作用,确保治疗过程的安全、有效、经济。

OBJECTIVE： To investigate the role of clinical pharmacists in pediatric severe infection treatment, and to provide reference for rational drug use in clinic. METHODS： Based on related typical cases, the breakthrough points of clinical pharmacists providing pharmaceutical care in pediatric severe infection treatment plan were introduced. RESULTS： Clinical pharmacists formu- lated multi-drug resistance pathogenic antibacterial plan according to the results of pathogenic microbiological examination, use pharmacokinetics/pharmacodynamics, excluded interference to pediatric anti-infection treatment from ADR, and guideline and economical factors of patients. CONCLUSIONS： Clinical pharmacists adopt professional knowledge of pharmacy to provide pharmaceu- tical care in pediatric severe infection treatment and play professional assisted role so as to guarantee safe, effective and economical treatment.