心力衰竭治疗中β-受体阻滞剂的应用研究

Clinical effect of β-blockers in treatment of heart failure

目的对心力衰竭治疗中β-受体阻滞剂的应用效果进行观察、总结和分析。方法以我院2015年8月到2016年8月接收的52例慢性心力衰竭患者为研究对象,随机分为观察组和对照组,各26例。其中对照组患者采用常规内科治疗,而观察组患者在此基础上加用β-受体阻滞剂(美托洛尔)。对比两组患者的临床效果。结果观察组患者的治疗有效率明显高于对照组,且各项血流动力学指标均优于对照组,差异均具有统计学意义(P<0.05)。结论心力衰竭治疗中应用β-受体阻滞剂的总体效果显著,能够显著提升心功能,改善患者的预后,值得广泛应用。

Objective To investigate the clinical effect of β-blockers in the treatment of heart failure. Methods A total of 52 patients with chronic heart failure who were admitted to our hospital from August 2015 to August 2016 were enrolled and randomly divided into observation group and control group, with 26 patients in each group. The patients in the control group were given conventional medical treatment, and those in the observation group were given the β-blocker metoprolol in addition to the conventional medical treatment. The clinical outcome was compared between the two groups. Results Compared with the control group, the observation group had a significantly higher response rate and significantly better hemodynamie parameters （P〈0.05）. Conclusion β-Blockers have a marked effect in the treatment of heart failure and can significantly improve patients＇ cardiac function and prognosis. Therefore, it holds promise for elinical application.