射血分数正常的心力衰竭患者NT-proBNP水平与血红蛋白的相关性分析被引量：3

Study on correlation between NT-proBNP level and hemoglobin in patients with heart failure complicating preserved ejection fraction

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摘要目的探讨射血分数正常的心力衰竭(HFpEF)患者氨基末端脑钠肽前体(NT-proBNP)水平与血红蛋白(Hb)的相关性。方法测定该院2015年10月至2016年8月收治的283例HFpEF住院患者入院时的NT-proBNP、Hb水平,进行相关性分析。结果 (1)HFpEF患者中,贫血患者NT-proBNP水平与Hb呈负相关(r=-0.278,P<0.05),而非贫血患者NT-proBNP水平与Hb之间无相关性(P>0.05);(2)HFpEF患者中,NT-proBNP与Hb相关性的变化趋势不受性别影响。结论 HFpEF患者应联合检测NT-proBNP与Hb,从而为临床诊治心力衰竭提供一定的依据。 Objective To investigate the relationship between the N-terminal pro-brain natriuretic peptide（NT-proBNP）level and hemoglobin（Hb）in the patients with heart failure complicating preserved ejection fraction（HFpEF）.Methods The levels of NT-proBNP and Hb in 283 HFpEF inpatients admitted in our hospital from October 2015 to August 2016 were measured and performed the correlation analysis.Results（1）Among HFpEF patients,the NT-proBNP level was negatively correlated with Hb level in anemic patients（r=-0.278,P0.05）,had no correlation with the Hb level in non-anemic patients（P0.05）;（2）Among HFpEF patients,the change trend in the correlation between NT-proBNP and Hb was not affected by gender.Conclusion HFpEF patients should conduct the combined detection of NT-proBNP and Hb for providing some basis in clinical diagnosis and treatment of heart failure.

作者李鑫任明岗常盼王建榜王西辉吴娟张学策张静于军

机构地区西安医学院第二附属医院心血管内科/陕西省心血管内科疾病临床医学研究分中心

出处《检验医学与临床》 CAS 2017年第17期2495-2496,2499,共3页 Laboratory Medicine and Clinic

基金国家自然科学基金资助项目(81470438 81270329) 陕西省教育厅科研计划项目(16JF023 16JK1667) 西安医学院心血管内科校级重点建设学科资金资助项目

关键词射血分数心力衰竭氨基末端脑钠肽前体血红蛋白 ejection fraction heart failure NT-proBNP Hb

分类号 R541 [医药卫生—心血管疾病]

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参考文献1

1赵志坤,曲峰,郭旗,刘润梅,李良,翟红霞,殷亚昕,张津津,夏云峰.贫血对左心室射血分数保留型心力衰竭患者生存状况的影响[J].中华老年心脑血管病杂志,2015,17(9):942-944. 被引量：5

二级参考文献10

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