2012—2016年南京市第二医院甘草酸类抗肝炎药物的门诊使用情况分析

Analysis on the utilization of glycyrrhizic acid anti-hepatitis drugs in outpatient department of the Second Hospital of Nanjing from 2012 to 2016

目的了解南京市第二医院2012—2016年甘草酸类抗肝炎药物的门诊使用情况,分析该类药物的使用特点和趋势,为临床合理用药和科学管理提供参考。方法收集南京市第二医院2012—2016年甘草酸类药物的门诊使用资料,对消耗量、销售金额、用药频度(DDDs)、日均费用(DDC)进行分析。结果 2012—2016年,从消耗量和销售金额来看,甘草酸二铵所占构成比最大,且逐年递增,在2016年分别占到74.70%、69.52%;从DDDs排序来看,复方甘草酸苷制剂和甘草酸二铵分别排在前两位,其DDC分别排在第5、3位,DDC最高的是异甘草酸镁注射液。结论南京市第二医院门诊治疗肝炎以第3代的甘草酸类药物甘草酸二铵制剂为主,这与其低廉的价格和适宜的用药频度是一致的。

Objective To investigate the utilization condition of glycyrrhizic acid anti-hepatitis drugs in outpatient department of the Second Hospital of Nanjing from 2012 to 2016, and to analyze the characteristics and tendency so as to provide references for the rational use and scientific management of glycyrrhizic acid drugs. Methods The consumption data of glycyrrhizic acid drugs in the Second Hospital of Nanjing from 2012 to 2016 were collected for analysis of consumption sum, sales amount, frequency of drug use （DDDs）, and average daily cost （DDC）, etc. Results From 2012 to 2016, consumption sum and sales amount of diammonium glycyrrhizinate accounted for the largest proportion, and increased year by year, accounted for 74.70% and 69.52% in 2016. From the point of view of DDDs sequencing, compound glycyrrhizic acid preparation and diammonium glycyrrhizinate were ranked in the top two, respectively, and DDC were ranked in the fifth and the third. DDC of Magnesium Isobutyrate Injection ranked the highest. Conclusion The third generation of glycyrrhizic acid preparation diammonium glycyrrhizinate is mainly used in outpatient department of the Second Hospital of Nanjing, which is consistent to its low price and appropriate frequency of medication.