高龄老年高血压合并体位性低血压患者的临床特点

Clinical Characteristics of Very Elderly Patients With Hypertension Combined With Orthostatic Hypotension

目的探讨高龄老年高血压合并体位性低血压患者的临床特点。方法本研究共纳入我院心内科2014年1月—2017年1月收住的高龄老年高血压患者160例,根据患者是否合并体位性低血压,分为OH组(n=56)及非OH组(n=104),比较两组主要临床基本资料及用药情况。结果与非OH组相比,OH组收缩压更高,舒张压更低,合并冠心病、糖尿病、焦虑抑郁状态比例更高,应用β-受体阻滞剂、钙拮抗剂、利尿剂、硝酸酯类、镇静睡眠药等药物比例更高,差异均有统计学意义(P<0.05)。结论高龄老年高血压患者发生体位性低血压与其基础疾病、服药情况密切相关。

Objective To explore the clinical characteristics of very elderly patients with hypertension （HT） combined with orthostatic hypotension （OH）. Methods A total of 160 cases of very elderly patients with HT combined with OH in Cardiology Department from January 2014 to January 2017 were enrolled in the present study. All the patients were divided into OH group （n=56） and non OH group （n=104） based on the presence of OH or not. The main clinical manifestation and medication were compared between two groups. Results OH group had a higher level of systolic blood pressure, and a lower level of diastolic pressure than non OH group. Compared with non OH group, OH group showed a higher rate of comorbidity including coronary heart disease, diabetes, anxiety and depression status, and had a higher proportion of medication of beta blockers, calcium antagonists, diuretics, nitrates, sleeping pill. The differences were statistically significant （P 〈 0.05）. Conclusion The occurrence of OH in very elderly patients with HT was closely related with the basic diseases and medication.