固肠止泻丸治疗药治疗脾胃虚弱型艾滋病腹泻临床分析

Clinical Analysis of Guchang Zhixie Pills in the Treatment of Spleen-stomach Deficiency of AIDS-induced Diarrhea

目的为有效治疗艾滋病腹泻患者,临床探究中药制剂固肠止泻丸用于治疗脾胃虚弱型患者的有效性。方法选取2011年7月—2015年7月期间甘肃省康泰医院门诊部门收治的艾滋病腹泻患者86例,该次临床分组采用双盲法随机将患者分为西药组43例、中西组43例。其中西药组腹泻者仅以西药进行治疗,中西组在此基础上加用中药制剂固肠止泻丸,对两组疾病治疗效果进行评估,同时对患者症状改善用时进行记录比较。结果中西组腹痛消失用时(2.62±0.73)d、大便性状正常(3.52±0.84)d、腹泻消失用时(3.83±0.64)d,西药组腹痛消失用时(3.86±1.37)d、大便性状正常(5.16±1.23)d、腹泻消失用时(4.62±1.25)d,中西组患者症状改善用时均少于西药组(P<0.05);中西组症状改善有效率为95.3%,西药组为83.7%,西药组较中西组疗效差(P<0.05)。结论临床对于脾胃虚弱型艾滋病腹泻者,在使用西药治疗时加用中药制剂固肠止泻丸,能提高治疗效果、促进患者症状改善。

Objective This paper tries to explore the clinical effect of Guchang Zhixie pills of TCM for spleen-stom-ach deficiency of AIDS-induced diarrhea and to effectively cure these patients. Methods 86 patients with AIDS-in-duced diarrhea treated from July 2011 to July 2015 in this hospital were selected and randomly divided into two groups by double-blind method, with 43 cases in each group. The western medicine group just took western medicine; while the combined group took the combined therapy of western medicine and Guchang Zhixie pills of TCM. The clinical ef-fect and clinical symptoms of both groups were recorded. Results The disappearance time of stomachache was （2.62± 0.73） d, normal stool property of （3.52±0.84） d and disappearance of diarrhea of （3.83±0.64） d in the combined group, and those in the western medicine group of （3.86±1.37） d, （5.16±1.23） d, （4.62±1.25） d （ P〈0.05）; the clinical effective rate of the combined group was 95.3%, higher than that of the western medicine group of 83.7%, the clinical effect of the western medicine group was worse than the combined group （ P〈0.05）. Conclusion For patients with spleen-stomach deficiency of AIDS-induced diarrhea, the combined therapy of western medicine and Guchang Zhixie pills of TCM can improve the clinical effect and clinical symptoms.