喜炎平注射液治疗尘肺反复肺部感染发作的效果分析

Analysis of effect of Xiyanping injection in the treatment of pneumoconiosis recurrent pulmonary infection attack

目的研究喜炎平注射液治疗尘肺反复肺部感染发作的效果。方法此次研究纳入的对象来源于2013年2月至2015年12月该院收治尘肺反复肺部感染发作患者中随机抽取的83例。将上述83例尘肺反复肺部感染发作患者随机分为常规组41例和喜炎平组42例。常规组采用常规吸氧、祛痰、止咳、平喘等治疗，并给予头孢派酮舒巴坦静滴，喜炎平组在常规组基础上增加喜炎平注射液治疗。比较（1）尘肺反复肺部感染发作缓解率；（2）恶心呕吐等不良反应发生率；（3）干预前和干预后患者氧分压和二氧化碳分压等血气分析相关指标的差异。结果（1）喜炎平组较之常规组尘肺反复肺部感染发作缓解率更高（P〈0．05）；（2）两组患者恶心呕吐等不良反应发生率无显著差异（P〉0．05）；（3）干预前两组氧分压和二氧化碳分压等血气分析相关指标相似（P〉O．05）；干预后喜炎平组较之常规组氧分压和二氧化碳分压等血气分析相关指标改善更显著（P〈0．05）。结论喜炎平注射液治疗尘肺反复肺部感染发作的效果确切，可有效控制肺部感染发作，改善患者血气分析，药物作用安全，无严重副作用，值得推广。

Objective To study the effect of Xiyanping injection in the treatment of pneumoconiosis onset of recurrent pulmona- ry infection. Methods the subjects o^r this study were randomly selected from 83 patients with pneumoconiosis recurrent pulmonary infection attack in our hospital from February 2013 to December -2015. The above 83 cases of pneumoconiosis recurrent pulmonary infection patients were randomly divided into the treatment group of 41 cases and 42 cases of Xiyanping group. The conventional group received routine oxygen, expectorant, antitussive and antiasthmatic treatment, and given cefoperazone sulbactam intravenous- ly,Xiyanping group increased Xiyanping injection treatment in the conventional group on the basis of. Comparison of pneumoconio- sis （1） recurrent pulmonary infection remission rate; （2） the incidence of adverse reactions such as nausea and vomiting; （3） the difference before and after intervention in patients with oxygen and carbon dioxide partial pressure and blood gas analysis index. Re- suits （1） compared with the conventional group,Xi Yanping group had higher pneumoconiosis pulmonary infection remission rate （P〈0.05） ; （2） there was no significant difference in adverse reactions such as nausea and vomiting incidence rate of the two groups （P〉O. 05） ; （3） before the intervention, the oxygen and carbon were similar （P〉O. 05） fthe oxygen and carbon dioxide partial dioxide partial pressure and gas analysis the index of two groups pressure and blood gas analysis index intervention of Xi Yanping group improved more significantly compared with the conventional group（P〈O. 05）. Conclusion Xiyanping injection in the treat- ment of pneumoconiosis recurrent pulmonary infection attack effect can effectively control the onset of pulmonary infection,improve the blood gas analysis and drug safety,and there was no serious side effects,thus it＇s worthy of promotion.