儿童节细胞神经瘤的CT、MRI特征

CT and MRI Characteristics of Ganglioneuroma in Children

目的:探讨儿童节细胞神经瘤的CT、MRI特征,旨在提高对其认识。方法:回顾性分析病理证实的38例儿童节细胞神经瘤的CT、MRI资料。结果:38例患儿中男女比例为1:1.8,平均年龄6.07±2.47岁。肿瘤位于后纵隔14例(36%),腹膜后间隙14例(36%),肾上腺8例(21%),颈部及盆腔各1例。肿瘤表现为类圆形、边界清晰的肿块,平扫CT图像显示大部分肿瘤表现为均匀低密度,CT值为22~38HU(平均30.5HU);MRI扫描图像显示,病灶于T1WI呈等信号为主或稍低信号,T2WI呈不均匀高信号,增强扫描动脉期病灶以不强化为主,门脉期可见轻中度强化。结论:节细胞神经瘤的CT及MRI表现具有一定的特征性,CT平扫均匀低密度,T2WI上呈不均匀高信号,肿瘤增强扫描后动脉期无强化,门脉期可见轻度或中度强化。

Purpose： To investigate the CT and MRI features of ganglioneuroma （GN） in children. Methods： CT and MRI features of 38 GNs confirmed by pathology results in our hospital were analyzed retrospectively. Results： In total 38 cases, the male to female ratio was 1：1.8, the mean age was 6.07±2.47 years old. Fourteen cases （36%） were located in the posterior mediastinum,14 cases （36%） in the retroperitoneal space, 8 cases （21%） were originated from adrenal gland, and 1 case located in the neck and pelvic region, respectively. Most tumors presented as an oval-shaped, well-defined mass on both CT and MR images. Tumors showed predominantly low attenuation on unenhanced CT images, with the CT value ranged from 22 to 38 HU （mean 30.5 HU）. Tumors showed homogeneous hypo-intense on T1-weighted images and heterogeneous hyper-intense on T2- weighted images. No enhancement or mild enhancement was noted in the arterial phase, and mild or moderate enhancement was shown in the portal venous phase on both CT and MR images. Conelusion： Ganglioneuroma in children are hypo-density on plain CT. On CT and MRI, no enhancement or slight enhancement in artery phase, and mild or moderate enhancement in the portal venous phase are characteristic manifestations of ganglioneuroma in children.