32例老年肺炎患者抗生素合理用药的临床效果研究

Clinical effect of rational use of antibiotics in 32 elderly patients with pneumonia

目的探讨老年肺炎患者临床中使用抗生素的特点以及合理用药情况，提出用药建议，以便于指导临床具体实践。方法选取本院2016年6月至2017年1月期间收治的老年肺炎患者32例，利用回顾性分析方法，针对所研究对象的抗生素使用情况进行统计分析，以判断临床用药的合理性，总结出控制耐药性发生的方法，提高临床老年肺炎治愈率。结果针对老年肺炎的患者临床抗生素使用种类达到16种，同时还搭配了具有抗菌效应的中药制剂，普遍利用联合用药方案，临床治愈率达37．5％，好转率为62．5％。结论对于老年肺炎患者的抗生素使用应该选取高效、高敏的药物，主要依据病原学检查以及药敏试验结果，同时严格遵循药物代谢动力学以及药效学，针对不良反应进行合理的用药，切实有效实施药物监护，力争最佳疗效。

Objective To explore the clinical use of antibiotics in elderly patients with pneumonia and the rational use of drugs, put forward the medication recommendations to guide the clinical practice. Methods 32 elderly patients with pneumonia admitted in our hospital from June 2016 to January 2017 were collected,the antibiotic use of the patients was analyzed by retrospective analysis method in order to judge the rationality of clinical medication, sum up the way of controlling drug resistance, improve the cure rate of clinical elderly pneumonia. Results For elderly patients with pneumonia, there were 16 kinds of antibiotics in clinical use, accompanied by traditional Chinese medicine preparations with the antibacterial effect, the combination therapy program was common, the clinical cure rate was 37.5%, the improvement rate was 62.5%. Conclusions For elderly patients with pneumonia, antibiotic medication should select highly efficient and sensitive drugs, mainly based on pathogen examination and drug sensitivity test results, strictly follow the pharmacokinetics and pharmacodynamics, make a reasonable medication for adverse reactions, and make an effective implementation of drug monitoring, to strive for the best effect.