HPLC法测定食品接触材料中BPA迁移量的不确定度评定

Uncertainty Evaluation for the Determination of Bisphenol A Migration of Food Contacted Materials by HPLC

参考GB/T 23296.16-2009《食品接触材料高分子材料食品模拟物中2,2-二(4-羟基苯基)丙烷(双酚A)的测定高效液相色谱法》测定食品接触材料(金属空罐)的双酚A迁移量。通过分析测定过程中的各种不确定度来源,计算各不确定度分量,得出金属空罐的双酚A迁移量为0.005 53 mg/dm^2,扩展不确定度为0.000 38 mg/dm^2。比较各不确定度分量大小可知,高效液相色谱法测定食品接触金属空罐双酚A迁移量的不确定度主要来自双酚A标品的纯度和标准曲线的拟合。

To base on GB/T 23296.16-2009, the bisphenol A migration in food contacted materials（metal cans） was determined. By analyzing and calculating the various sources of uncertainty during the entire deter-mination process , the amount of the bisphenol A migration in metal cans was 0.00553 mg/dm 2 with expanded uncertainty of 0.00038 mg/dm2.Comparison the amount of each uncertainty, the uncertainty of the bisphenol A migration in food contacted materials（metal cans） determined by HPLC mainly came from the purity of bisphe-nol A and the fitting of standard curve.