分子印迹磁性固相萃取/GC-MS法检测大米中三环唑

Analysis of Tricyclazole in Rice Sample Using Magnetic Molecularly Imprinted Polymers Solid-phase Extraction Combined with GC-MS

以表面分子印迹技术合成了三环唑的磁性分子印迹聚合物微球(Fe_3O_4@SiO_2-MIPs),建立了分子印迹磁性固相萃取/GC-MS法检测大米中三环唑的新方法。结果表明,在优化条件下Fe_3O_4@SiO_2-MIPs对三环唑有良好选择性,在0.050-8.0 mg·L^(-1)浓度范围内线性关系良好(r^2=0.9937),样品加标回收率86.31%97.69%,相对标准偏差小于5%。该方法高效快速、选择性好,可用于大米中痕量三环唑的检测。

Magnetic molecularly imprinted polymer microspheres of tricyclazole were synthesized by the surface molecular imprinting technique. A new method was established for the determination of tricyclazole in rice sample by molecularly imprinted magnetic solid-phase extraction/GC-MS. The results showed that F%O4@ SiO2-MIPs had a high selectivity for tricyclazole under the optimized experimental conditions. The calibration curve of tricyclazole was linear in the range of 0. 050 - 8.0 mg · L-1 with a correlation coefficient （ rE = 0. 9937 ）. The proposed method was successfully applied in the determination of tricyclazole in rice sample, with average recoveries of 86.31% ~ 97.69% and relative standard deviations （RSDs） less than 5%. The developed method is rapid and selective, and is adaptable to the analysis of trace tricyclazole in rice sample.