喜炎平联合双歧杆菌治疗小儿病毒性腹泻的临床观察

Clinical effect of Xiyanping injection combined with bifidobacterium in the treatment of infantile virus diarrhea

目的 探究喜炎平联合双歧杆菌联合治疗小儿病毒性腹泻的临床疗效.方法 选取病毒性腹泻患儿80例,采用随机数字表法分为对照组和研究组,每组各40例,对照组静脉滴注利巴韦林进行治疗,研究组静脉滴注喜炎平同时联用双歧杆菌进行治疗,观察并比较两组患者的症状消失时间（止泻时间、退热时间）、住院时间以及临床疗效情况.结果 研究组止泻时间、退热时间、住院时间分别为（2.19 ±0.43）d、（1.75士0.36）d、（4.13±0.85）d,明显少于对照组的（4.89±0.61）d、（3.68±0.52）d、（7.91±1.13）d,差异均有统计学意义（t=22.89、19.30、16.90,均P＜0.01）.研究组治疗总有效率为97.5％,对照组治疗总有效率为72.5％,差异有统计学意义（χ2=24.5,P＜0.01）.结论 喜炎平与双歧杆菌联合治疗小儿病毒性腹泻时患儿的止泻时间、退热时间、住院时间均明显缩短,临床疗效显著,建议临床上推广应用.

Objective To explore the clinical effect of Xiyanping injection combined with bifidobacterium in the treatment of infantile virus diarrhea.Methods 80 cases of infantile virus diarrhea were selected,they were randomly divided into control group and research group according to the digital table,40 cases in each group.The control group received intravenous drip ribavirin treatment,the research group received treatment of intravenous drip Xiyanping injection combined with bifidobacterium at the same time.The symptoms disappear time（time of diarrhoea,antifebrile time）,length of hospital stay and clinical curative effect were observed and compared between the two groups.Results The indicator of symptoms disappear time （time of diarrhoea,antifebrile time） and length of hospital stay of the research group were （2.19 ±0.43）d,（1.75 ±0.36）d,（4.13 ±0.85）d,respectively,which were shorter than those of the control group [（4.89 ± 0.61） d,（3.68 ± 0.52） d,（7.91 ± 1.13） d],the differences were statistically significant（t =22.89,19.30,16.90,all P 〈 0.01）.The total effective rate of the research group was 97.5%,which was significantly higher than 72.5% of the control group （χ2 =24.5,P 〈 0.01）.Conclusion Xiyanping injection combined with bifidobacterium in the treatment of infantile virus diarrhea has significantly shorter antidiarrheal time,antifebrile time,length of hospital stay than ribavirin,the clinical curative effect is distinct,which is worthy of clinical popularization and application.