绍兴地区573例慢性荨麻疹过敏原检测结果分析

目的研究绍兴地区导致慢性荨麻疹的过敏原种类，为临床预防和治疗提供依据。方法采用德国Mediwiss敏筛（allergyscreen）过敏原免疫印迹定量检测系统对573例慢性荨麻疹患者进行血清总IgE和过敏原特异性IgE检测。结果573例慢性荨麻疹，总IgE阳性221例（38．57％），其中检测有特异性IgEFe性302例（52，71％）。阳性率最高的前三位过敏原分别为户尘螨28．27％，点青霉、分枝孢菌、烟曲霉、交链孢菌18．32％，矮豚草、蒿律草10．12％。结论绍兴地区慢性荨麻疹的患者，过敏原以尘螨和真菌为主。找出致病原因对临床治疗慢性荨麻疹有很好的指导意义。

Objective To research varieties of allergens that cause chronic urticaria in Shaoxin, and provide references for clinical prevention and treatment. Methods Serum total IgE and allergens specific IgE in 573 chronic urticaria patients were detected by Mediwiss sensitive screening allergens quantitative detection system. Results The positive rates of tIgE and sIgE were 38.57% （ 221cases ） and 52.71% （ 302cases ） respectively in 573 cases. The top three allergens were dust mites 28.27%, fungus 18.32%, grass 10.12%. Conclusion In Shaoxin, the main allergens are dust mites and fungus. Identifying the causative factors is of instructive significance for the clinical treatment of chronic urticaria.