系统性硬化症消化道受累诊疗进展

Progress of gastrointestinal involvement in systemic sclerosis

系统性硬化症是一种以皮肤增厚为特征的自身免疫性疾病,消化系统为仅次于皮肤的第二大受累器官,其临床表现不特异,早期易被忽视,从而影响患者预后及生存质量.本文将对近几年系统性硬化合并消化系统并发症在病理、临床特征、患者管理及治疗方面的现状及进展进行综述,旨在提高内科医生尤其风湿病及消化等专业医生对该病的重视程度,以达到早期诊治及早改善预后的目的.

Systemic sclerosis is an autoimmune disease characterized by skin thickening and tightness.Digestive system is the most commonly damaged system secondary to skin,and as to unspecific clinical manifestations,this complication is often ignored in the early,the prognosis and quality of life of patients will be affected.This article overviews the recent research developments on pathology,clinical features,management of systemic sclerosis with digestive system involvement,to draw attention to early diagnosis and treatment of this condition for the improvement of the prognosis.