银屑病与真菌及真菌感染的关系研究新进展

Correlations of psoriasis with fungi and fungal infection

银屑病是一种常见的慢性炎症性皮肤病，发病率较高，病因复杂多样，发病机制尚未完全明了，严重影响患者心身健康和生活质量。近来研究发现，真菌及真菌感染可能是银屑病发生发展过程中的影响因素之一，可以互相影响，甚至有些治疗银屑病的生物制剂会诱发真菌感染。故有必要了解熟悉念珠菌、马拉色菌及皮肤癣菌与银屑病的相互关系及鉴别诊断。就这些病原真菌与银屑病关系的相关研究新进展进行概述，以期为银屑病的学术研究提供借鉴。

Psoriasis is a common chronic inflammatory skin disease, with high incidence, complex etiology and unclear pathogenesis. It can severely affect the physical and mental health and the quality of life of patients. Recent studies have found that fungi and fungal infection may be one of factors influencing the occurrence and development of psoriasis. Psoriasis and fungal infection can affect each other. Even some biological agents for the treatment of psoriasis can cause fungal infection. Thus, it is necessary to understand the correlations of psoriasis with Candida, Malassezia and dermatophytes, as well as their differential diagnosis. This review summarizes new progress in correlations of pathogenic fungi with psoriasis, providing reference for psoriasis-related researches.