眼底血管分级与急性脑梗死患者临床预后的相关性分析

Correlation analysis of retinal vessels grades and clinical prognosis in patients with acute cerebral infarction

目的探讨眼底血管分级与急性脑梗死患者临床预后的相关性。方法选择2015年3月至2016年2月神经内科住院的急性脑梗死患者180例,于入院3d内分别行眼底照相检查及神经功能缺损程度评分。根据2014版中国急性缺血性脑卒中诊治指南治疗3个月,采用改良Rankin量表评分分为转归良好组和转归不良组,分析眼底血管分级与急性脑梗死患者临床转归的关系。结果急性脑梗死患者眼底血管分级越高,神经功能缺损程度越重,差异有统计学意义(Hc=16.06,P<0.05)。转归良好组患者眼底病变分级较轻,转归不良组患者眼底血管分级较重,两组间比较差异有统计学意义(Uc=3.05,P<0.05)。结论急性脑梗死患者眼底血管分级与预后存在紧密联系:眼底血管分级越高,病情程度越重,且预后越差。

Objective To explore the correlation of retinal vessel grades and clinical prognosis in patients with acute cerebral infarction.Methods A total of 180 patients with acute cerebral infarction whom admitted in the Department of Neurology,Xiaoshan Hospital of Traditional Chinese Medicine were collected from March 2015 to February 2016.All patients were examined with fundus digital photography and the neural function impairment scores within three days after admission.All patients were treated according to 2014 edition of the guidelines of diagnosis and treatment of acute ischemic stroke,and evaluated with the modified Rankin Scale （mRS） after three months.They were divided into good outcome group and poor outcome group according to the modified Rankin scale score.To analysis the correlation of retinal veddel grades with clinical prognosis in patients with acute cerebral infarction.Results （①According to the method of rank sum test Kruskal-Wallis,the higher retinal vessels grades in patients with acute cerebral infarction,the heavier the degree of neural function impairment.To comparison the different retinal vessels grades,there was statistical difference （Hc=16.06,P〈0.05）.②） According to the rank sum test Wilcoxon two sample comparison method,good outcome group of retinal vessels grades is lighter in patients with acute cerebral infarction,and poor outcome group of retinal vessels grades is heavier,there was statistical difference between the two groups （Uc=3.05,P〈0.05）.Conclusion Retinal vessels grades and prognosis of acute cerebral infarction patients is closely linked：The higher retinal vessels grade,the heavier the degree of illness,and the worse prognosis.