弯孢聚壳属真菌次级代谢产物及其生物活性

Secondary metabolites from Eutypella species and their bioactivities

本文对弯孢聚壳属真菌的化学成分和生物活性进行综述。目前从弯孢聚壳属真菌中发现的次级代谢产物类型主要包括二萜、细胞松弛素类、倍半萜、单萜、甾体、内酯类等。这些化学成分显示出抗肿瘤、抗菌、免疫抑制的活性。

This review summarizes the chemical constituents and bioactivities of the secondary metabolites from species of the genus Eutypella. Seventy-six natural products have been reported from the fungi including diterpenoids, cytochalasins, sesquiterpenoids, monoterpenoids, steroids and lactones. These chemical constituents exhibit various bioactivities such as anti-tumor, antibacterial action and immunosuppressive activity