应用噬菌体保障即食食品安全的研究进展

Advances in phage therapy for controlling the safety of ready-to-eat food

即食食品的出现与普及为人们的生活创造了极大便利,由于其无需加热即可食用,无法对潜在致病菌进行有效杀灭,从而引发诸多食品安全问题,危害人类健康。噬菌体能高效特异识别并裂解宿主菌,这一特性使其被认为是最具潜力的抗生素替代品。研究人员则利用噬菌体特异裂解微生物这一特性,在保障即食食品安全方面进行了一系列的研究,并开发了针对即食食品病原菌的噬菌体产品,用于防控即食食品在加工和包装过程中可能受到的污染。本文则对噬菌体在保障即食食品安全方面的研究进展进行综述。

The presence of ready-to-eat food provides significant benefits and convenience for human life. Nevertheless, potential pathogens can not be cleaned up effectively, because ready-to-eat food are consumed without heating. Many outbreaks of foodborne diseases have been found to be associated with pathogens in ready-to-eat food. They are considered as an emergent public health concern throughout the world. Bacteriophages are bacterial viruses with many properties, such as high specificity and shorter screening period. For this reason, more and more interests have been stimulated in the alternative approach of using lytic phages for treatment or prophylaxis of bacterial infections in the processing and packaging of ready-to-eat food. This review aimed to emphasize the effects of lyric phages in eliminating the contamination of ready-to-eat food.