应用极速成像技术早期评价代谢综合征患者颈动脉硬化

The early evaluation of carotid atherosclerosis in patients with metabolic syndrome by Ultrafast imaging

目的:应用极速成像技术(Ultrafast imaging,UltraFast^(TM))评价代谢综合征(MS)患者颈动脉弹性早期改变。方法:选取MS组48例,代谢异常组55例,正常组50例。检测双侧颈总动脉内-中膜厚度(IMT),UltraFast^(TM)检测脉搏波传导速度(PWV),包括收缩期起始时PWV(PWV-BS)及收缩期结束时PWV(PWV-ES)。结果:代谢异常组与正常组间IMT、PWV-BS及PWV-ES无差异(P>0.05),而MS组IMT、PWV-BS、PWV-ES均高于正常组及代谢异常组(P<0.05)。结论:MS患者颈动脉弹性减低,UltraFast^(TM)通过测量颈动脉PWV可成为一种早期快速评估MS患者颈动脉硬化的新方法。

Objective： To assess the application value of Ultrafast imaging for the early evaluation of carotid functional change in patients with metabolic syndrome. Methods： There were 48 metabolic syndrome cases（metabolic syndrome group）, 55 metabolic abnormality cases（metabolic abnormality group） and 50 healthy cases（control group）. The inter-media thickness（IMT） and pulse wave velocity（PWV）, including the PWV at the beginning of the systole（PWV-BS） and the PWV at the ending of the systole（PWV-ES）, were evaluated. Results： IMT, PWV-BS and PWV-ES in the metabolic syndrome group were higher than those in the control group and metabolic abnormality group（P〈0.05）. Those were no difference between the metabolic abnormality group and control group（P〉0.05）. Conclusion： The carotid artery elasticity in patients with metabolic syndrome decreased. The UltraFast technique is expected to be a new method to early rapidly evaluate the carotid atherosclerosis in patients with metabolic syndrome.