多灶性骨坏死

Multifocal oteonecrosis

多灶性骨坏死(MFON)定义是指同时或相继累及三个及以上独立解剖部位的骨坏死,MFON临床上比较少见,约占骨坏死人群的3%,多数MFON典型表现为6个关节受累。引起MFON的主要原因为应用皮质类固醇。MFON最常累及股骨头,其次为膝关节、肩关节和距骨等,对有高危因素的骨坏死患者,应警惕MFON的存在,必要时增加其他关节的影像学筛查,以期实现MFON的早诊断早治疗。

Multifocal osteonecrosis（ MFON） is defined as disease involving three or more separate anatomic sites concurrently or consecutively. It is a rare clinical condition,which is found to occur in approximately 3% of patients with osteonecrosis. Typically,most patients have about six joints involved.Corticosteroid use is often reported as the most common risk factor in 90% of patients with multifocal osteonecrosis. In multifocal osteonecrosis,femoral head involvement is found to occur most commonly,followed by the knee,shoulder,and talus. For patients with high-risk factors,attention should be paid to MFON. It is necessary to increase the other joints of the imaging screening to avoid missed diagnosis. This will be beneficial to get early diagnosis and reasonable treatment,which will help to obtain the best clinical results.