实时剪切波弹性成像对慢性乙型肝炎肝脏纤维化的诊断价值

Diagnostic value of supersonic shear imaging evaluating the degree of liver fibrosis in chronic hepatitis B

目的探讨实时剪切波弹性成像(SWE)对慢性乙型肝炎(CHB)患者肝脏纤维化程度的诊断价值。方法收集2015年1月至2016年12月在滨州医学院附属医院就诊的慢性HBV感染的患者125例,以肝脏穿刺活检的病理学检查结果为金标准,应用SWE技术检测肝脏的弹性模量值,分析患者的弹性模量值与病理学的相关性。结果不同程度肝组织炎症活动度患者的弹性模量值存在明显差异,不同肝脏纤维化程度患者的弹性模量值存在明显差异。结论 SWE通过测量肝脏的弹性模量值能对肝脏纤维化进行量化分析,能够为临床CHB患者提供一种简单、无创的肝脏纤维化程度的评估手段。

Objective To explore the value of supersonic shear imaging evaluating the degree of liver fibrosis in chronic hepatitis B. Methods Data of 125 patients in a hospital. from Jan. 1,2015 to Dec. 12,2016 were collected, and Pathological examination results from Liver biopsy were taken as the gold standard. SWE was used to test the elastic modulus and The elastic modulus was compared with pathological stages of hepatic fibrosis. Results There was significant differences in the elastic modulus of patients with different degrees of inflammation activity of liver tissue and of liver fibrosis. Conclusion SWE imaging was promising for clinical applieation and could be utilized as a noninvasive method for the quantitative evaluation of fibrosis staging in chronic hepatitis.