老年黄斑变性玻璃体腔注射康柏西普治疗的临床效果分析

Senile Macular Degeneration Glass Body Cavity Injection of Compaq Heap Analysis of Clinical Effect of Treatment

目的:探讨老年黄斑变性玻璃体腔注射康柏西普的临床效果。方法:回顾性分析2016年1月—2017年1月在我院治疗的老年性黄斑变性(湿性)的患者60例(60眼),根据纳入标准及随机数字表法分为研究组(接受1次玻璃体腔注射康柏西普治疗)和对照组(接受1次玻璃体腔注射曲安奈德治疗),各30例(30眼)。对比两组术前、治疗1个月和6个月最佳矫正视力及黄斑中心凹视网膜厚度,并记录治疗前后的并发症情况。结果:两组术前最佳矫正视力及黄斑中心凹视网膜厚度比较差异无统计学意义(P>0.05);观察组治疗1个月和6个月最佳矫正视力均高于对照组,黄斑中心凹视网膜厚度均低于对照组,差异均有统计学意义(P<0.05)。结论:玻璃体腔注射康柏西普治疗老年黄斑变性疗效肯定,并发症低,值得临床推广。

Objective：To investigate senile macular degeneration glass body cavity injection of compaq heap clinical effect.Methods：Patients with age-related macular degeneration in our hospital were randomly divided into two groups,each group of 30 cases（30 eyes）：the study group（treated with intravitreal injection of conbercept once）and the control group（treated with intravitreal injection of triamcinolone acetonide once）.The best corrected visual acuity and foveal retinal thickness were compared between the two groups before treatment and 1 month and 6 months after treatment,and recorded before and after treatment of complications.Results：There was no significant difference between the two groups in preoperative best corrected visual acuity and foveal retinal thickness（P〈0.05）.There was a significant difference between the two groups in best corrected visual acuity and foveal retinal thickness before treatment and 1 month and 6 months after treatment（P〈0.05）.Conclusion：Glass body cavity injection of compaq heap curative effect on senile macular degeneration,low complications and worthy of clinical promotion.