温石棉致病性及相关流行病学研究进展

Carcinogenicity of chrysotile:Pathogenesis and epidemiologic studies

石棉分为温石棉和角闪石类石棉两类。目前对于温石棉潜在致癌、致纤维化的能力还存在争议。为了全面归纳和提炼温石棉的致病性情况,对温石棉的致癌和致纤维化机制、温石棉致病影响因素(包括空气中温石棉浓度、形态、可溶性以及工人吸烟与否)、温石棉所致职业性肿瘤流行病学研究、温石棉同角闪石类石棉致病性差异的流行病学研究、温石棉致病机制的研究方向及展望进行了分析。

Chrysotile is one type of asbestos. The potential pathogenicity of chrysotile is currently a controversial issue. This article discussed the carcinogenic and fibrotic mechanisms of chrysotile,its etiological factors（including fiber concentration,form,durability and so on）and the epidemiologic study results,so that we can understand clearly the health hazards of chrysotile.