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骨质疏松症的病因病机研究概况 被引量:16

Study on the Etiology and Pathogenesis of Osteoporosis
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摘要 近年来,骨质疏松症的发病率逐年升高,严重影响人们的健康和生活质量。其发病机制复杂多样,且早期阶段症状不明显,多半在发生损伤性骨折后被发现。目前,临床治疗主要以西药为主,效果明显,但西药具有不良反应大、价格昂贵的特点。因此,研究骨质疏松症的发病因素及探索其他更有效的预防与治疗方法显得十分必要。未来结合现代生活方式与临床疾病研究,整理总结出骨质疏松症的发病因素,及可引发骨质疏松症的其他疾病,将为临床主要以非药物治疗为主提供理论基础。 In recent years, the incidence of osteoporosis has been rising year by year, which seriously affects the people's health and quality of life. The pathogenesis of the osteoporosis is complex and diverse, and the early stage symp- toms are not obvious, and most of them are found after traumatic fracture. Currently, the main clinical treatment is western medicine, which has obvious effect, but also is featured with greater adverse effect and high cost. Therefore, it is necessary to study the pathogenesis of osteoporosis and explore other methods of prevention and treatment. The future clinical disease research combining modern lifestyle, to summarize the risk factors of osteoporosis and other diseases which can cause osteo- porosis, will provide a theoretical basis for the main non-drug therapy in clinical.
作者 杨芳芳 马慧萍 葸慧荣 高玉海 YANG Fangfang MA Huiping XI Huirong GAO Yuhai(Department of Pharmacy Department of Orthopedics Research Institute, Lanzhou General Hospital, Lanzhou 730050, China)
出处 《医学综述》 2017年第18期3599-3603,共5页 Medical Recapitulate
基金 国家自然科学基金(81471090)
关键词 骨质疏松症 生理因素 疾病因素 生活方式 Osteoporosis Physiological factors Disease factors Lifestyle
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