2012年浙江省玉环县农村社区成年人早发2型糖尿病影响因素

Related factors for early-onset type 2 diabetes mellitus of rural adults in Yuhuan County of Zhejiang Province in 2012

目的探索农村社区早发2型糖尿病影响因素。方法 2012年6—12月,在浙江省玉环县随机整群抽取的3个农村社区居民中开展了玉环成年人糖尿病队列基线调查,选取其中的1695例新诊断2型糖尿病患者为研究对象,根据诊断年龄是否大于40岁分为早发2型糖尿病和迟发2型糖尿病,比较不同特征的诊断年龄,并用Logistic回归分析早发2型糖尿病发生的相关因素。结果在1695例新诊断2型糖尿病中,5.0%(85例)为早发2型糖尿病,47.3%为男性,平均诊断年龄为(60.39±12.49)岁。男性、初中及以上文化程度、家庭人均月收入≥2000元、从事轻体力活动职业、吸烟、饮酒、超重和有糖尿病家族史的患者诊断年龄较低,参加规律体育锻炼(62.52岁vs 59.93岁)的2型糖尿病诊断年龄较高。多因素Logistic回归分析显示,在校正其他因素后,与迟发2型糖尿病相比,初中及以上文化程度(OR=6.62,95%CI 3.87~11.32)、家庭人均月收入≥2000元(OR=6.60,95%CI 3.32~13.12)、规律体育锻炼(OR=0.37,95%CI 0.17~0.80)是早发2型糖尿病发生的独立相关因素。结论文化程度、家庭人均月收入、规律体育锻炼与玉环县农村社区居民早发2型糖尿病密切相关。

Objective To explore related factors for early-onset type 2 diabetes mellitus（ EOD） in rural Chinese adults. Methods Totally,1695 newly diagnosed cases of type 2 diabetes mellitus（ T2DM） were recruited from baseline survey of Yuhuan Rural Adults Cohort for Diabetes during June to December 2012 in Yuhuan County,Zhejiang Province,China,and divided into EOD or late-onset type 2 diabetes mellitus（ LOD） with their diagnosis age at ≤ 40 or 40 years,respectively. Diagnosis age was compared among different characteristics. Logistic regression was used to analyze related factors in EOD. Results Among 1695 new T2 DM cases,near half（ 47. 3%） were men and 85（ 5. 0%） were grouped into EOD. Their mean age at diagnosis of T2 DM was（ 60. 39 ±12. 49） years overall. Men or those with more than 9 education years,family average personal income ≥2000 Yuan per month,less occupational physical activities,smoking,drinking,overweight and family history of T2 DM had lower average age at diagnosis than women or those without them,while those with regular physical exercise had higher that than those without that. After the adjustment for other covariates, multiple logistic regression showed that more than 9 education years（ OR = 6. 62,95% CI 3. 87-11. 32）,family average personal income ≥2000 Yuan per month（ OR = 6. 60,95% CI 3. 32-13. 12）,and regular physical exercise（ OR = 0. 37,95% CI 0. 17-0. 80） were independently correlated to EOD. Conclusion Education level,income,and regular exercise are significantly correlated to EOD in rural Chinese adults.