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右美托咪定与咪达唑仑治疗胸科老年人麻醉术后谵妄的效果比较 被引量:4

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摘要 目的探讨右美托咪定与咪达唑仑(力月西)在胸科老年人麻醉术后谵妄的临床效果。方法将76例胸外科老年手术患者随机分为观察组和对照组各38例,两组均给予芬太尼持续静脉泵入镇痛,对照组首次静脉推注力月西0.05mg/kg,随后以0.02~0.08 mg·kg^(-1)·h^(-1)维持麻醉,观察组首次静脉推注右美托咪定1.0μg/kg,然后以0.2~0.7μg·kg^(-1)·h^(-1)维持麻醉,比较两组镇静效果和不良反应发生。结果两组镇静效果时间均无统计学差异(P>0.05);但观察组停药后苏醒时间短于对照组,不良反应发生率低于对照组(P<0.05)。两组手术后SDS及SAS评分明显低于干预前,且观察组明显低于对照组(P<0.05)。结论右美托咪定用于胸外科老年手术中的镇静效果好,且降低不良反应发生率。
出处 《中国老年学杂志》 CAS 北大核心 2017年第18期4598-4599,共2页 Chinese Journal of Gerontology
基金 国家科技支撑计划(2012BAK21B01-02-2)
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