个旧市孕妇维生素D水平对妊娠结局的影响研究

Effect of vitamin D level in pregnant women in Gejiu city on pregnancy outcome

目的研究观察个旧市孕妇妊娠期间维生素D水平对妊娠结局的影响。方法以2016年1月‐2016年12月来该院进行产前检查的个旧市孕妇675例为研究对象,对受试对象的基本信息和产检孕妇的维生素D水平进行检查,根据检查结果将受试孕妇分为维生素D充足组、不足组及缺乏组,观察各组孕妇的妊娠结局并进行组间比较。结果 (1)维生素D充足、不足、缺乏3组孕妇的维生素D水平值检测结果分别为(43.29±10.21)、(20.47±9.51)、(6.57±3.01)ng/ml。(2)维生素D缺乏组患者妊娠结局包括流产、早产、剖宫产及胎儿窘迫的发生率显著高于其他两组患者(P<0.05)。(3)缺乏组患者妊娠期间细菌性阴道病、贫血、妊娠期高血压及糖尿病的发生率高于其他两组患者(P<0.05)。结论孕妇妊娠期维生素D缺乏对妊娠结局有影响,增加流产、剖宫产及窘迫胎儿的发生率,并且会增加妊娠期妇女的相关疾病的发生率。

【Objective】To study the effect of vitamin D level in pregnant women in Gejiu city during pregnancy on pregnancy outcome.【Methods】A total of 675 cases of pregnant women in Gejiu city who went to our hospital for prenatal examination during January 2016 and December 2016 were selected as research objects,basic information and prenatal vitamin D levels of the subjects were examined,and according to the inspection results the subjects were divided into vitamin D sufficient group,vitamin ？D insufficient group and vitamin D deficiency group.The pregnancy outcomes of pregnant women in each group were observed and compared among the three groups.【Results】The level of vitamin D of the pregnant women in vitamin D sufficient group,vitamin ？D insufficient group and vitamin D deficiency group were（43.29 ± 10.21）,（20.47 ± 9.51） and（6.57 ± 3.01） ng/ml.The incidences of abortion,premature delivery,cesarean section and fetal distress in vitamin D deficiency group were significantly higher than those in the other two groups（P〈0.05）.The incidences of bacterial vaginosis,anemia,pregnancy induced hypertension and diabetes during pregnancy in vitamin D deficiency group were significantly higher than those in the other two groups（P〈0.05）.【Conclusion】The lack of vitamin D in pregnant women has an effect on the outcome of pregnancy,which can increase the incidence of abortion,cesarean section and fetal distress,and increase the incidence of related diseases in pregnant women.