干燥性角结膜炎应用普拉洛芬滴眼液治疗的临床研究

To Investigate the Clinical Efficacy of Pilocarpine Eye Drops in the Treatment of Dry Keratoconjunctivitis

目的观察并探讨普拉洛芬滴眼液治疗干燥性角结膜炎临床疗效。方法选取我院2016年2月至2017年2月期间门诊就诊并治疗的80例确诊为干燥性角结膜炎的患者为研究对象,随机分为实验组40例和对照组40例。实验组给予聚乙烯醇滴眼液联合普拉洛芬滴眼液治疗,对照组给予聚乙烯醇滴眼液治疗。对比两组患者临床效果及泪膜破裂时间。结果经两种方法治疗后,实验组的总有效率明显高于对照组(92.50%VS 75%)。对照组主观症状平均评分明显低于对照组,实验组的泪膜破裂时间明显比对照组延长。结论普拉洛芬滴眼液治疗干燥性角结膜炎的临床效果显著,能够明显改善患者的临床症状,值得在临床上推广。

Objective To observe and explore the clinical efficacy of pramlofen eye drops in the treatment of dry keratoconjunctivitis.Methods Eighty patients with dry keratoconjunctivitis were randomly divided into experimental group（n=40）and control group（n=40）.The patients were randomly divided into experimental group（n=40）.The rats in the experimental group were treated with polyvinyl alcohol eye drops and prazolafine eye drops.The control group was treated with polyvinyl alcohol eye drops.Comparison of two groups of patients with clinical effects and tear film rupture time.Results The total effective rate of the experimental group was significantly higher than that of the control group（92.50% vs 75%）after treatment by two methods.The average score of the subjective symptoms in the control group was significantly lower than that in the control group.The tear film rupture time in the experimental group was significantly longer than that in the control group.Conclusion The clinical effect of pramlofen eye drops on the treatment of dry keratoconjunctivitis is remarkable,which can obviously improve the clinical symptoms of patients and is worthy of clinical promotion.