肌酸激酶同工酶在心肌损伤中的研究进展

Research Progress of Creatine Kinase Isoenzyme CK-MB in Myocardial Injury

肌酸激酶同工酶(CK-MB)作为心肌损伤的重要酶学检测指标,颇受临床重视。目前,其常用检测方法有免疫抑制法、酶质量法和电泳法,以免疫抑制法测CK-MB活性最为常用,然而一些生理性及病理性因素常致CK-MB活性假性增高,这给临床上心肌损伤的诊断产生干扰。本文就CK-MB在心肌损伤中的研究进展作以下综述。

Creatine kinase isoenzyme CK-MB,as an important enzyme detection index of myocardial injury,which is attached importance to clinic.Recently,the commonly used test methods include immunosuppression,CK-MB mass and electrophoresis,and the most frequently-used method to measure CKMB activity is immune suppression.However,some physiological and pathological factors often lead to increased CK-MB activity,which may interfere with the diagnosis of myocardial injury.This article will reviews the progress of CK-MB in myocardial injury.