基于子午流注理论观察中药润肠膏穴位贴敷改善慢性阻塞性肺疾病患者便秘的疗效评价

Curative effect of Ziwu Liuzhu theory-based acupoint application of Runchang Gao on constipation in patients with chronic obstructive pulmonary disease

目的基于子午流注理论观察中药润肠膏穴位贴敷对慢性阻塞性肺疾病患者便秘的疗效分析.方法选取2015-06/2017-03在义乌市中医医院呼吸科住院的104例慢性阻塞性肺疾病便秘患者作为研究对象,按照住院顺序编号,随机分为对照组和观察组,2组各52例.对照组给予口服麻仁丸,观察组在对照组基础上基于子午流注理论给予自制润肠膏敷贴于神阙穴,1次/d,连续治疗1 wk.观察患者临床疗效,临床症状变化和不良反应情况.结果治疗后观察组总有效率明显高于对照组(92.30%vs 73.08%),差异有统计学意义(P<0.05).2组治疗后排便困难,粪便性状,排便时间,下坠、不尽、胀感、排便频度、腹胀等评分均较治疗前降低,差异有统计学意义(P<0.05),且观察组明显低于对照组.2组治疗后咳嗽、咯痰、喘息及啰音评分均较治疗前降低,差异有统计学意义(P<0.05),且观察组明显低于对照组.结论子午流注理论指导中药润肠膏穴位贴敷能改善慢性阻塞性肺疾病便秘患者的临床疗效和症状评分变化,值得临床推广应用.

AIM To evaluate the curative effect of Ziwu Liuzhutheory-based acupoint application of Runchang Gao on constipation in patients with chronic obstructive pulmonary disease.METHODS One hundred and four chronic obstructive pulmonary disease patients with constipation treated at our hospital from June 2015 to March 2017 were included and randomly divided into either a control group（n = 52） or an observation group（n = 52）. Both groups were given oral Maren pills, and the observation group was additionally given Runchang Gao that was applied on the CV8 acupoint（once daily for 1 wk） based on the Ziwu Liuzhu theory. Clinical efficacy, symptoms, and adverse reactions were observed in the two groups.RESULTS The total effective rate was significantly higher in the observation group than in the control group（92.30% vs 73.08%, P 〈 0.05）. The scores of constipation symptoms such as difficulty in defecation, defecation time, and defecation frequency were significantly reduced after treatment in both groups（P 〈 0.05）, and the reduction was more significant in the observation group than in the control group. After treatment, scores of respiratory symptoms such as cough, phlegm, wheezing, and rumbling were significantly improved in both groups（P 〈 0.05）, and the improvement was more significant in the observation group than in the control group.CONCLUSION Ziwu Liuzhu theory-based acupoint applicationof Runchang Gao can significantly improve constipation and respiratory symptoms in chronic obstructive pulmonary disease patients with constipation.