射频消融在手术切除术后复发性小肝细胞癌中的应用

Application of radiofrequency ablation for recurrent small hepatocellular carcinoma after hepatectomy

外科手术切除治疗肝细胞癌(hepatocellular carcinoma,HCC)虽可作为部分患者的首选治疗,但术后患者的5年复发率仍高达70%,5年生存率不足50%。对于复发性肝癌的治疗,国内外尚未达成共识。由于大多数复发性肝癌是直径小于3 cm的结节,射频消融(radiofrequency ablation,RFA)治疗能够达到与二次外科手术切除相似的结局,且具有创伤小、并发症少、术后恢复快、住院时间短等优点。本文对RFA治疗复发性小HCC进行讨论,以期为更好地治疗手术切除后复发的小HCC提供理论依据。

Hepatectomy is one of the curative therapies for hepatocellular carcinoma（HCC）. However, the 5-year recurrence rate after resection is higher as 70%, and the 5-year survival rate is less than 50%. Furthermore, there is no consensus about the treatment strategy for recurrent HCC after hepatectomy. To our knowledge, radiofrequency ablation（RFA） has been widely applied, either with curative or palliative intention. And it is a feasible treatment for recurrent HCC because of majority of the recurrent HCCs with diameter less than 3 cm. The therapeutic efficacy after RFA is similar to re-resection with several advantages, such as minimal invasion, less complications and short hospitalization duration. This study discusses the feasibility of RFA which is used to treat recurrent small HCC, aiming at providing information for promoting the treatment efficacy of recurrent small HCC.