幼年型强直性脊柱炎的MRI表现研究

MRI manifestations of juvenile-onset ankylosing spondylitis

目的探讨幼年型强直性脊柱炎(juvenile-onset ankylosing spondylitis,Jo AS)的MRI表现特点,以提高对该病的诊治水平。方法回顾性分析2010年10月—2014年9月经临床及实验室证实的25例Jo AS患者的MRI图像。结果 25例患者的67个病变部位包括骶髂关节(19个)、髋关节(21个)、髂嵴(6个)、坐骨结节(6个)、膝关节(9个)、踝关节(4个)及足部(2个)。MRI表现为骨髓水肿63个,关节积液36个,骨质破坏26个,附着点炎19个。结论骨髓水肿是Jo AS最常见的MRI表现,骨质破坏以中轴关节为主。MRI显示病变敏感但缺乏特异性,需注意鉴别诊断。

Objective To explore the MRI features of juvenile-onset ankylosing spondylitis （JoAS） for improving the level of diagnosis and therapy. Methods MRI findings of JoAS in 25 patients confirmed by clinical and laboratory results between October 2010 and September 2014 were retrospectively analyzed. Results There were a total of 67 locations of lesion in the 25 cases, including 19 in sacroiliac joint, 21 in hip joint, 6 in ischial tuberosity, 6 in crista iliaca, 9 in knee joint, 4 in ankle joint, and 2 in foot. MRI showed 63 locations with bone marrow edema, 36 with joint effusion, 26 with bone destruction, and 19 with enthesitis. Conclusions Bone marrow edema is the most common MRI manifestation of JoAS, and the main bone destruction is middle axis joint. MRI is sensitive but not specific to lesions, so differential diagnosis is needed and helpful.