颈动脉斑块积分对冠状动脉病变的预测价值

The Predictive Value of Carotid Plaque Score for Evaluating the Severity of Coronary Artery Lesions

目的:研究颈动脉斑块积分对冠状动脉(冠脉)病变的预测价值。方法:选取2016-01至2016-05在我院进行冠脉造影检查,并且最终确诊为冠心病的152例患者。根据病变累及冠脉情况,将所有患者分为单支病变组72例、双支病变组38例和多支病变组42例,收集患者斑块检出率、高密度脂蛋白胆固醇(HDL-C)、体重指数(BMI)等基本情况,并对所有患者进行颈动脉超声检查,按照半定量积分法则和Gensini积分法则分别计算颈动脉斑块情况和冠脉病变程度,将半定量积分和Gensini积分进行比较,寻找两者之间的联系。结果:各组间总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、HDL-C、BMI等基本指标差异无统计学意义(P>0.05)。但双支病变组和多支病变组患者的吸烟人数和斑块检出率要明显高于单支病变组(P<0.05)。同时颈动脉的半定量积分及冠脉Gesini积分均随着病变支数的增加而增加。结论:根据颈动脉斑块半定量积分可以对冠心病严重程度进行预测和分析。

Objective： To study the predictive value of carotid plaque score for evaluating the severity of coronary artery lesions. Methods： A total of 152 patients with coronary angiography diagnosed coronary artery disease （CAD） in our hospital from 2016-01 to 2016-05 were selected. According to coronary branch involvement, the patients were divided into 3 groups： Single branch lesion group, n：=72, Double branch lesion group, n=38 and Multi branch lesion group, n=42. The basic conditions as plaque detection rate, high-density lipoprotein cholesterol （HDL-c）, body mass index （BMI） were collected and carotid ultrasound examination was conducted in all patients. Carotid plaque condition and coronary lesion degree were calculated by semi-quantitative score and Gensini score methods; the relationship between semi-quantitative score and Gensini score was compared. Results： Total cholesterol （TC）, HDL-C, LDL-C and BMI were similar among different groups, P〉0.05. Compared with Single branch lesion group, Double branch lesion group and Multi branch lesion group had more smokers and the higher plaque detection rate, P〈0.05. Semi-quantitative score and Gensini score were elevating as coronary lesion branch increasing accordingly. Conclusion： The severity of coronary lesions could be evaluated and predicted by semi-quantitative calculation of carotid integral.