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Ki-67、PR在Luminal型乳腺癌中的表达及预后意义 被引量:3

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摘要 Luminal型乳腺癌是最常见的乳腺癌亚型.虽然预后相对较好,但复发转移仍严重威胁女性健康。Ki-67是判断乳腺癌细胞增殖活性主要指标,孕激素受体(progesterone receptor,PR)则具有调节乳腺癌生长和分化的功能。PR缺失可能是恶性增殖和激素治疗抵抗因素之一。近年Ki-67、PR逐渐成为乳腺癌预后及分型热点指标,但仍倍受争议。本文回顾性分析Ki-67、PR在Luminal乳腺癌中的表达及预后意义,为该型乳腺癌个体化治疗提供一定理论依据。
出处 《中华普通外科杂志》 CSCD 北大核心 2017年第9期787-788,共2页 Chinese Journal of General Surgery
基金 上海市科委基金资助项目(14411950205,15411962700)
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