抗凝联合穴位按摩对剖宫产术后下肢深静脉血栓的治疗效果

The effect of anticoagulation combined with acupoint massage for treating women with lower extremity deep venous thrombosis after caesarean section

目的:分析和比较抗凝联合穴位按摩应用于剖宫产术后下肢深静脉血栓(LEDVT)的疗效。方法:选择本院2010年1月-2016年10月剖宫产术后发生LEDVT的患者100例,随机分为对照组53例,观察组47例,对照组给予抗凝治疗,观察组在对照组治疗方法基础上给予穴位按摩,比较两组治疗前后的肢围、超声血管内径、血流速度、出凝血指标及疗效和安全性。结果:两组治疗前膝盖以上15cm和膝盖以下10cm的肢围、血管内径、血流速度、纤维蛋白原(FIB)、D-二聚体(D-Dmier,D-D)、凝血酶时间(TT)、凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)和血小板(PLT)均无统计学差异(P>0.05),治疗后观察组的血凝指标均有所改善,总有效率高于对照组(P<0.05),两组治疗期间无严重的出血事件。结论:抗凝联合穴位按摩可提高剖宫产术后LEDVT的治疗效果,可能与改善凝血指标和凝血功能有关。

Objective：To analyze and compare the effect of anticoagulation combined with acupoint massage for treating women with lower extremity deep venous thrombosis（LEDVT）after caesarean section.Methods：From January 2010 to October 2016,100 women with LEDVT after caesarean section in the first hospital of Jilin university were randomly divided into control group（n=53）and observation group（n=47）.The women in control group were given anticoagulant therapy,and the women in observation group were given anticoagulant combined with acupoint massage.The limb perimeter,blood vessel diameter,blood flow velocity,coagulation index and coagulation function,and safety of women were compared before and after treatment.The curative effect and safety of women were also compared between the two groups.Results：There were no significant differences in the limb perimeter,blood vessel velocity,blood flow velocity,and level of fibrinogen（FIB）,D-dimer（D-D）,thrombin time（TT）,prothrombin time（PT）,activated partial thromboplastin time（APTT）and platelet（PLT）of women between the two groups before treatment（P〈0.05）.After treatment,compared with the women in control group,the level of FIB,DD or PLT was significantly lower（P〈0.05）,and the diameter of blood vessel,blood flow velocity,level of TT,PT and APTT of women were significantly higher than those of women in the observation group（P〈0.05）.The rate of effective of women in the control group were lower than that of women in the observation group（P〈0.05）,and there was no any woman with serious bleeding in both groups.Conclusion：Anticoagulation combined with acupoint massage can be used for treating of LEDVT after caesarean section by optimizing coagulation index and coagulation function.