摘要
丁型肝炎病毒(HDV)是乙型肝炎病毒(HBV)的卫星病毒,呈世界性流行,其感染和复制与HBV感染存在密不可分的联系。我国是HBV感染的高发国家之一,HBV相关研究较多,但对其卫星病毒HDV的研究较少。我们较全面地梳理了HDV的分子生物学特征、流行病学特点、实验研究模型、检测、预防及治疗几个方面的最新进展,期望对未来HDV的研究起到一定的推动作用。
Hepatitis D virus（HDV）, the satellite of hepatitis B virus（HBV）, is a worldwide human pathogen. The infection and replication of HDV are inseparable with HBV. China is one of the countries with high incidence of HBV infection, and many research projects focus on HBV but few on its satellite virus HDV. In this review, the latest developments in HDV molecular biology, epidemioiogical characteristics, experimental models, detection, prevention and treatment were introduced and summarized comprehensively. We hope this paper can play a certain role in the future study of HDV.
出处
《生物技术通讯》
CAS
2017年第4期558-563,共6页
Letters in Biotechnology
基金
国家高技术研究发展计划青年科学家项目(2015AA020946)
