体外循环心脏手术应用自体血液回输效果研究

The effects of autologous blood transfusion in extracorporeal circulation cardiac surgery

目的探讨自体血液回输用于体外循环(ECC)心脏手术的效果。方法选入2014年10月至2016年10月在本院行ECC心脏手术的患者60例,随机分为对照组和观察组,每组30例,分别采用异体血和自体血回输。比较两组血液指标变化及不良反应情况。结果观察组术后24 h血红蛋白、血小板、红细胞计数、凝血酶原、凝血酶时间和纤维蛋白原均明显高于对照组(P<0.05),而异体输血总量、术后24 h纵膈引流量以及并发症总发生率均显著低于对照组(P<0.05)。结论 ECC心脏手术应用自体血液回输可有效节约库血,同时避免异体输血可能引起的血液性传染病及各种并发症。

Objective To investigate the effects of autologous blood transfusion in extracorporeal circulation （ECC） cardiac surgery.Methods 60 patients received ECC cardiac surgery from October 2014 to October 2016 were randomly divided into control group and observation group,30 cases in each,allogeneic and autologous blood transfusion were used respectively.Changes of blood indexes and adverse reactions were compared between the two groups.Results The levels of Hb,Plt,RBC,PT,TT and FIB 24 hours after surgery in observation group were significantly higher than those in control group （P〈0.05）,and the total amount of allogeneic blood transfusion,postoperative 24 h mediastinal drainage and the total incidence of complications were significantly lower than those of control group （P〈0.05）.Conclusion Autologous blood transfusion for ECC cardiac surgery can save the bank blood and avoid blood borne infectious diseases as well as various complications effectively which may be caused by allogeneic blood transfusion.