胃癌患者术前PG-SGA评分与人体成分的相关性

Correlation between preoperative PG-SGA score and body composition in patients with gastric cancer

目的探讨胃癌患者术前主观整体评估(PG-SGA)评分与人体成分的相关性。方法选择天津市第三中心医院2015年6月至2016年10月收治的82例胃癌患者为研究对象,均进行PG-SGA量表评估及人体成分测定,PG-SGA量表得分为0~3分者纳入营养良好组(n=25),4分以上者纳入营养不良组(n=57)。比较两组患者人体成分指标,以及PG-SGA评分与人体成分指标的相关性。结果营养不良组患者的体质量、体质量指数(BMI)、体脂肪量、体脂百分比、瘦体组织、身体水分含量、细胞外液量分别为(51.92±6.85)kg、(18.58±1.92)kg/m2、(13.32±3.15)kg、(14.19±4.05)%、(44.13±4.96)kg、(33.02±2.64)L、(12.27±1.38)L,均明显低于营养良好组的(62.95±11.32)kg、(23.45±1.86)kg/m2、(15.87±3.32)kg、(23.37±3.31)%、(47.18±5.23)kg、(34.75±3.21)L、(13.72±1.37)L,差异均有统计学意义(P<0.05);PG-SGA评分与体质量、BMI、体脂肪量、体脂百分比、蛋白质含量、瘦体组织、体细胞量、骨骼肌量、身体水分含量、细胞外液、细胞内液均呈负相关性(P<0.05)。结论 PG-SGA与人体成分指标具有较好的相关性,术前进行PG-SGA评分及人体成分测定对评估胃癌患者的营养状况和营养干预方案的制定具有重要的临床意义。

Objective To investigate the correlation between Patient-Generated Subjective Global Assessment（PG-SGA） score and body composition in patients with gastric cancer before operation. Methods A total of 82 cases of patients with gastric cancer, who admitted to our hospital from June 2015 to October 2016, were selected as the research object. The PG-SGA scale evaluation and determination of body composition were carried out, patients with score of 0-3points enrolled into the normal nutrition group（n=25）, more than 4 points enrolled into the malnutrition group（n=57）.The PG-SGA score and human body composition indicators of the two group were compared, and the correlation between PG-SGA score and body composition index was assessed. Results The body weight, body mass index（BMI）, body fat mass, body fat percentage, lean body mass, body water content and extracellular fluid volume in the malnutrition group were（51.92±6.85） kg,（18.58±1.92） kg/m^2,（13.32±3.15） kg,（14.19±4.05）%,（44.13±4.96） kg,（33.02±2.64） L,（12.27±1.38） L, respectively, which were significantly lower than corresponding（62.95±11.32） kg,（23.45±1.86） kg/m^2,（15.87±3.32） kg,（23.37 ± 3.31）%,（47.18 ± 5.23） kg,（34.75 ± 3.21） L,（13.72 ± 1.37） L in the normal nutrition group（P〈0.05）.PG-SGA score was negatively correlated with body composition including weight, BMI, body fat, body fat percentage and the content of protein, lean body mass and body cell mass, skeletal muscle mass, body water content and extracellular fluid and intracellular fluid（P〈0.05）. Conclusion PG-SGA has a good correlation with the human body composition index. Preoperative PG-SGA score and body composition determination have important clinical significance in assessing the nutritional status and nutritional intervention of patients with gastric cancer.