摘要
目的探讨个性化饮食对2型糖尿病患者血小板反应蛋白-1(TSP-1)的影响及效果分析。方法选取医院收治的2型糖尿病患者112例,随机分为对照组与观察组,各56例。在原药物治疗方案不变的基础上,对照组接受常规饮食宣教与糖尿病饮食,观察组接受个性化饮食管理、远程随访等护理干预,对比两组治疗前与治疗后12个月的TSP-1水平及临床效果。结果治疗护理12个月后,对照组FBG和2h PBG水平较治疗前改善,观察组BMI、FBG、2h PBG、Hb A1c和TSP-1水平均较治疗前改善(P<0.05),且治疗后观察组BMI、FBG、2h PBG、Hb A1c、TSP-1水平均低于对照组(P<0.05)。此外,观察组治疗后糖尿病自护行为量表(SDSCA)评分显著高于对照组(P<0.05)。结论个性化饮食护理管理能够降低2型糖尿病患者血清TSP-1水平,有效控制血糖、BMI等指标,改善患者饮食治疗依从性,有较好临床应用价值。
Objective To explore the impacts and effects of individualized diet management on the thrombospondin-1 （TSP-1） in patients with type 2 diabetes mellitus. MeAods A total of 112 patients with type 2 diabetes mellitus admitted to our hospital were selected and randomly divided into an observation group and a control group （n =56, respectively）. On the basis of the original therapeutic scheme, the control group received regular diet education and diabetic diet and the observation group received individualized diet management, remote follow-up and other nursing intervention. The TSP-1 levels and effects 12 months before and after the treatment between the two groups were compared. Results 12 months after the treatment and nursing, the FBG and 2 h PBG levels in the control group were improved, and the BMI, FBG, 2 h PBG, HbA1c and TSP-1 levels in the observation group were also improved （P〈 0.05）; the post-treatment BMI, FBG, 2 h PBG, HbA1c and TSP-1 levels in the observation group were lower than those in the control group（ P〈 0.05）. In addition, the post-treatment scores of the scale of the diabetes self-care activities （SDSCA） in the observation group were significantly higher than those in the control group（P 〈 0.05）. Conclusion Individualized diet managementcan lower the TSP-1 levels in patients with type 2 diabetes mellitus, effectively control blood glucose, BMI and other indexes, and improve the diet therapy compliance of patients, so it has high clinical application value.
出处
《西南国防医药》
CAS
2017年第9期968-971,共4页
Medical Journal of National Defending Forces in Southwest China
